| Date | Opponent | Result/Time | Record | TV |
| September 1 | Youngstown State | W 38-6 | 1-0 | Big Ten Network |
| September 8 | Akron | W 20-2 | 2-0 | Big Ten Network |
| September 15 | at Washington | W 33-14 | 3-0 |   |
| September 22 | Northwestern | W 58-7 | 4-0 | |
| September 29 | at Minnesota | W 30-7 | 5-0 |  |
| October 6 | at No. 23 Purdue | W 23-7 | 6-0 |  |
| October 13 | Kent State | W 48-3 | 7-0 | Big Ten Network |
| October 20 | Michigan State | W 24-17 | 8-0 | |
| October 27 | at No. 25 Penn State | W 37-17 | 9-0 | |
| November 3 | No. 21 Wisconsin | W 38-17 | 10-0 | Big Ten Network |
| November 10 | Illinois | 3:30 PM ET | N/A | |
| November 17 | at No. 12 Michigan | 12:00 PM ET | N/A | |
No. 1 Ohio State looks to continue its march to a showdown with Michigan, but first it has to get through Illinois. The Buckeyes will likely be more prepared for the Illinois this year as opposed to last year when OSU won 17-10.
Go Bucks!
Go Bucks!
